What is Nasolabial Growth Factor Treatment?

Author
First in Western Japan,Specializing Clinic in Nasolabial Fold,Wrinkle Treatment
Osaka Houreisen Cosmetic Dermatology　
Chairman/Director
Shinya　Sasagawa　About Doctor

At our clinic, we inject “growth factors” into the nasolabial folds to improve the complexes of people who are troubled by nasolabial folds.

There are many different methods for treating nasolabial folds, so it’s no wonder that you want to get rid of them but don’t know what to do.

In the fields of esthetics, skin care, and cosmetic dermatology, you need to receive treatments regularly and repeatedly, which takes time, effort, and money, and in the field of cosmetic surgery, even if the treatment lasts for a long time, it is not something you can easily receive due to the risks and downtime, so there are pros and cons.

If you wanted to improve your nasolabial folds with cosmetic medicine, what would you prioritize?

The characteristics of the growth factor treatment we perform at our clinic are that it is a safe and easy treatment among the many nasolabial fold treatments, but unlike growth factor treatments performed at other clinics, it does not cause side effects such as lumps or continued swelling, and the effects are easy to feel after one treatment, lasts a long time, and has a natural finish.

It’s easy to administer, has little pain, and has short downtime, making it an easy treatment to receive even for those who are new to cosmetic medicine.

Over the long term, it offers better cost performance than other treatments.

At our clinic, we are meticulous about the formulation, composition, concentration, and injection method of “growth factors,” and we conduct daily research to determine how safe and effective the treatment is.

Here, we will explain in detail the effects and precautions of growth factor treatment, which is very popular among our patients.

What’s Growth factor？
Effect of growth factor treatment
Benefits of our nasolabial growth factor treatment
Disadvantages of Nasolabial Growth Factor Treatment
Procedures after visiting the hospital and required time
Differences between our growth factors and those of other clinics
Cost of Growth Factor Treatment
FAQ
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Related links
- About nasolabial folds
- グロースファクターについて

What’s Growth factor？

First of all, what are growth factors?

Growth factors are actually proteins that are naturally produced in the body.

Growth factors generally decrease rapidly as we reach adulthood, and then decrease even more as we age.

Why can growth factor injections be used to treat nasolabial folds?

There is a layer called the dermis inside the skin.

It gives the skin its firmness, luster and elasticity.

The main components of dermal tissue are skin-beautifying components such as collagen, elastin and hyaluronic acid.

The factory for these are cells called fibroblasts.

When the dermis is damaged by aging, ultraviolet rays, or dryness, collagen, elastin, and hyaluronic acid are also damaged.

Fibroblasts try to repair the skin by producing new collagen, elastin, and hyaluronic acid.

However, fibroblasts themselves are damaged and deteriorate, so they no longer function properly.

This causes skin aging, wrinkles, sagging, and the appearance of nasolabial folds.

Growth factor treatment activates and increases the number of these cells called fibroblasts.

This causes new production and proliferation of collagen, which is the source of firmness, luster, and elasticity, improving the appearance of nasolabial folds.

It also promotes skin turnover, improving the skin’s regenerative ability.

Effect of growth factor treatment

We would like to introduce you to the actual effects of Growth Factor.

We will show you some case photos of patients who have actually received Growth Factor treatment at our clinic.

Younger people’s nasolabial folds

Nasolabial folds that become more pronounced with age

Advanced sagging nasolabial folds

Male nasolabial folds

As you can see, Growth Factor can basically be used on any type of nasolabial fold.

Whether the nasolabial folds are still faint or have progressed, they can be improved regardless of age or gender.

We have many other case photos, so if you’re interested, please take a look.

Case photos of nasolabial fold growth factor injection

Benefits of our nasolabial growth factor treatment

The effect lasts for a long time

The effect lasts for at least several years with one treatment.

It is rare for a single treatment to have such long-lasting effects.

The growth factors themselves disappear after about six months, but the collagen significantly increased by the growth factors continues to

have an effect for a long period of time afterwards, resulting in a natural finish.

If viewed in 10-year increments, there is the effect of natural aging, but because growth factors have the effect of preventing wrinkles, there

will be a difference in appearance 10 years from now between receiving growth factors and not receiving them.

The effect lasts for at least several years with single treatment.

Case photos of nasolabial fold growth factor injection at long-term

よくあるご質問：貴院のグロースファクターは他院のグロースファクターに比べてなぜ持続期間が長いのですか？

No need for regular visits to the clinic

Those who with deep wrinkles may require multiple injections, but most people can feel effect with just one treatment.

It is extremely rare to find a clinic that offers growth factor treatments that can produce such noticeable results with just one treatment.

よくあるご質問：1回の治療で本当に効果が出てくるのですか？

Economical

Because the effects last for a long time with fewer treatment sessions, it is very economical compared to other nasolabial fold treatments.

For example, if you look at it in terms of a 10-year period, the difference in cost could be hundreds of thousands to millions of yen, although

this is just a rough estimate.

参考：ほうれい線治療にかかる治療費について

Treatment details	cost for ten years as a guideline
Growth Factor	180,000yen（If you take an additional treatment,it costs 270,000yen）
HIFU	1,200,000yen（The more you take HIFU, the more it costs）
Hyaluronic acid	700,000yen （The more you take hyaluronic acid injection, the more it costs）
Thread lift	1,000,000yen（same as above）

Virtually no downtime

You can continue your daily life as normal after the treatment.

There is little swelling or bruising, but if bruising does occur, it can be covered with makeup.

Makeup can be applied one hour after the treatment.

The photo below shows the condition of someone the day after receiving Growth Factor.

slightly red on the skin.

you see no redness.

Highly safe

It is highly safe and easy to undergo.

It is not a surgery, so it puts little strain on the body.

Growth factors are components that are naturally produced in our bodies and work to keep the skin young.

It is not an animal-derived component, so no one at our clinic has had an allergic reaction to it in the past.

Receiving growth factors will not impose any restrictions on you in the future, such as receiving placenta and not being able to donate blood.

By the way, hyaluronic acid injections, which are often performed to treat nasolabial folds, carry risks such as blindness and skin necrosis.

Growth factor injections are a medical procedure, so there are side effects and risks, but they are not serious risks.

At our clinic, we also provide growth factor treatment to family members and friends.

If growth factors were dangerous drugs, we would not perform the treatment on family members.

よくあるご質問：グロースファクターは安全ですか？

Has anti-aging effects

Collagen produced by growth factors improves skin quality by giving the skin firmness and lustre.

Increased collagen slows down the rate at which wrinkles and sagging occur. The areas where growth factors are injected will prevent future

aging, so having the treatment will make a difference in how you look 10 years from now compared to not having the treatment. It’s best to

have the treatment before wrinkles become more noticeable, as it will simply slow down the progression of nasolabial folds.

Case photos of 2 years after nasobalial growth factor injection

Two years after treatment, wrinkles will become more noticeable as the aging process progresses.

However, because growth factor treatment has been administered to the nasolabial fold area, it remains youthful compared to the untreated

areas around the mouth.

A fundamental treatment for nasolabial folds

decrease in collagen in the skin is seen as a cause of nasolabial folds in many people.

Growth factors, on the other hand, can improve the skin’s regenerative ability and restore collagen in the skin.

Being able to rejuvenate the skin itself is in a sense a fundamental wrinkle treatment.

Therefore, out of all the treatments for nasolabial folds, this is one that lasts particularly long.

Disadvantages of Nasolabial Growth Factor Treatment

The effect is not immediate

Unlike hyaluronic acid, growth factors do not have an immediate effect, but rather are a gradual treatment that produces results.

Immediately after treatment, the injected fluid will cause swelling and puffiness (edema), and the nasolabial folds will become thinner, but

once the swelling and puffiness subsides, the area will appear to have reduced volume.

The effects of treatment can be felt as early as one week after.

After that, your appearance will gradually become more youthful.

It is possible to see results like this in just one month.

※She is the author’s sister.

It will take about six months for you to finally get outcome.

Therefore, even if you want to receive additional injections, you cannot do so until at least six months have passed.

If you feel that hyaluronic acid is not enough, you can inject more in a short period of time, so in that respect it is easier to adjust the effect.

よくあるご質問：グロースファクターの効果はいつ頃から感じられますか？

Unlike hyaluronic acid, there are no dissolving enzymes

We have never had a patient who has received treatment at our clinic say they want to return to their original state before the treatment.

However, if you want to return to the original state before the treatment, with hyaluronic acid injections, it is possible to dissolve the

hyaluronic acid by injecting a hyaluronic acid-dissolving enzyme.

(However, dissolving the hyaluronic acid becomes more difficult over time after the injection.)

On the other hand, many injection treatments such as growth factors, fat injections, and PRP do not contain dissolving enzymes,

so it is difficult to completely restore the original state if you think it’s hyperplasia.

However, it is possible to partially fix it and the effect will decrease gradually.

よくあるご質問：グロースファクター治療を受けることでしこりが出るリスクがあると聞いたのですが、本当ですか？

Does not improve dark spots or dullness around the mouth

Growth Factor is effective against wrinkles and fine lines, but is not very effective against blemishes or dullness.

Effects vary from person to person

As with all treatments, results vary from person to person.

The effectiveness of growth factor treatment also varies from person to person.

However, I have never seen anyone who has had no effect at all from treatment, and more than 80% of patients are able to finish after one treatment.

However, some patients request additional injections because they want even greater results or feel unsatisfied.

This tends to happen to people who already have deep wrinkles or thick cheeks.

Additional injections incur a fee, but because the amount of medication needed is definitely less than the first injection, we offer them at a low price (under 90,000 yen) depending on the amount injected.

よくあるご質問：1回の治療で本当に効果が出てくるのですか？

よくあるご質問：『皮膚のコラーゲンを増やす』とありますが、不安点として想定以上に増えてしまうことはないのでしょうか？
万一そうなってしまった時の処置方法が気になるのですが、教えていただけますか？

Procedures after visiting the hospital and required time

①First, we provide a thorough medical examination and counseling.

②Photographs of the treatment area will be taken.

※This is to be viewed later when checking the effectiveness of treatment, and is not to be shown to third parties.

③Apply anesthetic cream to the injection site to thoroughly numb the area.

④After confirming that the anesthesia is working, the medicine is injected.

⑤Apply pressure to stop bleeding and prevent internal bleeding.

You are now home, thank you for your hard work.

The estimated time from arrival to departure is 1 hour for counseling alone, and approximately 2 hours 30 minutes including treatment (estimated).

Differences between our growth factors and those of other clinics

Other clinics also treat wrinkles using a substance called growth factor, but most clinics reduce the concentration and amount of growth factor injected per session, and require patients to visit the clinic multiple times to receive repeated injections.

Additionally, some people are concerned about the risk of lumps or hyperplasia in some areas.

However, at our clinic, we are extremely particular about our growth factor treatment.

We have been refining our treatment methods, using the best possible types of medication, carefully considered optimal concentrations, compounding methods, and injection methods, and we have devised unique methods to minimize risks while ensuring that patients see results in as little as one treatment.

I have performed this treatment on my family members in the past and it is safe.

We have treated over 1,000 nasolabial fold growth factors at our clinic, and fortunately we have never had a case where the patient ended up with an unnatural appearance.We provide thorough treatment with the aim of maintaining a natural finish for a long period of time.

If you are concerned about nasolabial folds, please come to our clinic.

To book a consultation or treatment, click here

Cost of Growth Factor Treatment

Nasolabial fold growth factor treatment.

￥180,000(Tax in)　※The price is for both sides, includes anesthesia, and there are no other costs.

￥100,000(Tax in)　※The price is for one side only, includes anesthesia. There are no other costs.

Compared to other nasolabial fold treatments, our growth factor treatment is very economical as it requires fewer treatment sessions and lasts longer.

参考：ほうれい線治療にかかる治療費について